Formulation: A solution in methanol at 100 µg/ml
Formal Name: N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl-2,2,4,4-d4]-glycine
Purity: ≥95%
Formula Markup: C26H39D4NO4
Formula Weight: 437,7
Shelf life (days): 1825
CAS Number: 2044276-16-4
Notes: Glycolithocholic acid-d4 is intended for use as an internal standard for the quantification of glycolithocholic acid (Item Nos. 21723 / 20273) by GC- or LC-MS. Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid (Item No. 20253).{48223} It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid (Item No. 15121).{30823} Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of PEG-obestatin(Cys10, Cys13), a modified peptide hormone, in lean or diet-induced obese mice.{32037} Serum glycolithocholic acid levels increase with age in children.{32038} Glycolithocholic acid-d4 MaxSpec® standard is a quantitative grade standard of glycolithocholic acid-d4 (Item No. 31308) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This glycolithocholic acid-d4 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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