HE-3235, CAS 183387-50-0

Formulation: A crystalline solid

Formal Name: (3α,5α,17α)-pregn-20-yne-3,17-diol

Purity: ≥95%

Formula Markup: C21H32O2

Formula Weight: 316,5

Shelf life (days): 730

CAS Number: 183387-50-0

Notes: HE-3235 is a synthetic adrenal hormone, an androstanediol analog, that acts as an androgen receptor antagonist.{32061} In an androgen receptor-dependent manner, it downregulates anti-apoptotic genes, while increasing the expression of pro-apoptotic genes, thus stimulating apoptosis.{32061} HE-3235 has been shown to inhibit androstenediol-dependent LNCaP cell tumor growth both in vitro (IC50 = 6 nM) and in xenograft models in vivo.{32061,32060}

• SKU: CAY9002769-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 9002769-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK