Formulation: A solid
Formal Name: 5-amino-4-oxo-pentanoic acid, hexyl ester, monohydrochloride
Purity: ≥95%
Formula Markup: C11H21NO3 • HCl
Formula Weight: 251,8
Shelf life (days): 1460
CAS Number: 140898-91-5
Notes: Hexaminolevulinate is a lipophilic, hexyl ester prodrug form of 5-aminolevulinic acid (Item No. 9001902).{40686} It produces equivalent protoporphyrin IX (PpIX) induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid. In vivo, hexaminolevulinate penetrates upper skin layers more effectively in pigs and induces higher levels of PpIX fluorescence in nude mice when compared with 5-aminolevulinic acid following topical administration.{40687} Formulations containing hexaminolevulinate have been used in imaging and photodynamic therapy for a variety of urogenital cancers.
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