Formulation: A crystalline solid
Formal Name: 21-(3-carboxy-1-oxopropoxy)-11β,17-dihydroxy-pregn-4-ene-3,20-dione, monosodium salt
Purity: ≥98%
Formula Markup: C25H33O8 • Na
Formula Weight: 484,5
Shelf life (days): 1460
CAS Number: 125-04-2
Notes: Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6).{29361} It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.{29362}