Formulation: A crystalline solid
Formal Name: (11β)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione
Purity: ≥98%
Formula Markup: C21H30O5
Formula Weight: 362,5
Shelf life (days): 1460
CAS Number: 50-23-7
Notes: Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH).{11860,47112} It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response.{47112} Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson’s disease.{11854,11861,47113}
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