Formulation: A solid
Formal Name: 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥95%
Formula Markup: C27H30O15
Formula Weight: 594,5
Shelf life (days): 1460
CAS Number: 32602-81-6
Notes: Kaempferol 3-neohesperidoside is a flavonoid that has been found in D. calycinum and has antioxidant and antidiabetic activities.{63161,63162,63163,63164} It scavenges DPPH (Item No. 14805) radicals in a cell-free assay (IC50 = 79.6 µg/ml).{63161} Kaempferol 3-neohesperidoside (1 and 100 nM) increases glucose uptake in isolated rat soleus muscle.{63162} It also increases glycogen synthesis in isolated rat soleus muscle, an effect that can be blocked by the PI3K inhibitor wortmannin (Item No. 10010591) and the MEK inhibitor PD 98059 (Item No. 10006726), when used at a concentration of 1 µM.{63163} Kaempferol 3-neohesperidoside (100 mg/kg) reduces serum glucose levels in a rat model of diabetes induced by alloxan (Item No. 9002196).{63164}
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