L-erythro Sphingosine (d18:1), CAS 6036-75-5

Formulation: A solid

Formal Name: (2R,3S,4E)-2-amino-4-octadecene-1,3-diol

Purity: ≥98%

Formula Markup: C18H37NO2

Formula Weight: 299,5

Shelf life (days): 1460

CAS Number: 6036-75-5

Notes: L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1) (Item No. 10007907). It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%) and superoxide generation induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in neutrophils as well as reduces growth of CHO cells (IC50s = 1.3 and 2 μM, respectively).{15200} L-erythro Sphingosine also inhibits dephosphorylation of the tumor suppressor retinoblastoma gene product (pRb; EC50 = 5 μM) and growth of MOLT-4 acute lymphoblastic leukemia cells (IC50 = 3.7 μM).{41482} [Matreya, LLC. Catalog No. 1826]

• SKU: CAY24372-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24372-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK