Formulation: A solution in ethanol
Formal Name: 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid, methyl ester
Purity: ≥95%
Formula Markup: C21H34O5
Formula Weight: 366,5
Shelf life (days): 365
CAS Number: 97643-35-1
Notes: Lipoxin A4 (LXA4) methyl ester is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.{352} LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 µM.{350} LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.{350,354,2722}