Maresin 2-d5

Formulation: A solution in ethanol

Formal Name: 13R,14S-dihydroxy-4Z,7Z,9E,11E,16Z,19Z-docosahexaenoic-21,21,22,22,22-d5 acid

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C22H27D5O4

Formula Weight: 365,5

Shelf life (days): 365

Notes: Maresin 2-d5 (MaR2-d5) contains 5 deuterium atoms at the 21, 21, 22, 22, and 22 positions. It is intended for use as an internal standard for the quantification of MaR2 (Item No. 16369) by GC- or LC-MS. MaR2 is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA.{26522} At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis of zymosan A by 90%.{26522}

• SKU: CAY20757-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 20757-50
• Green Labware: No
• Package Unit: 50 µg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung