Formulation: A solid
Formal Name: (11β,16α)-9,21-dichloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥90%
Formula Markup: C22H28Cl2O4
Formula Weight: 427,4
Shelf life (days): 1460
CAS Number: 105102-22-5
Notes: Mometasone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic activities.{61025,61026,61027} In vivo, mometasone (3 mg/kg) reduces pulmonary edema and neutrophil infiltration in a mouse model of chlorine-induced chemical lung injury.{61025} Intranasal administration of mometasone (0.2 µg/animal) reduces nose-rubbing behavior, sneezing, and nasal mucosal levels of IL-4 in a mouse model of allergic rhinitis.{61026} Mometasone also reduces nasal mucosal epithelial destruction, fibrosis, and cilia loss in a rat model of rhinitis medicamentosa induced by oxymetazoline (Item No. 23826).
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