Formulation: A solid
Formal Name: 9,21-dichloro-17-[(2-furanyl-3,4,5-d3-carbonyl)oxy]-11β-hydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C27H27Cl2D3O6
Formula Weight: 524,5
Shelf life (days): 730
Notes: Mometasone furoate-d3 is intended for use as an internal standard for the quantification of mometasone furoate (Item No. 21365) by GC- or LC-MS. Mometasone furoate is a prodrug form of the synthetic glucocorticoid mometasone (Item No. 31702).{33206} Intranasal administration of mometasone furoate (1 µg/nostril) reduces the frequency of sneezing and nasal rubbing in a rat model of histamine-induced allergic rhinitis.{61270} Topical application of mometasone furoate reduces croton oil-induced ear edema in mice (ED50 = 0.31 µg/ml).{61271} Formulations containing mometasone furoate have been used in the treatment of allergic rhinitis, atopic dermatitis, and asthma.
English
Deutsch
