Nervonic Acid, CAS 506-37-6

Formulation: A crystalline solid

Formal Name: 15Z-tetracosenoic acid

Purity: ≥95%

Formula Markup: C24H46O2

Formula Weight: 366,6

Shelf life (days): 1460

CAS Number: 506-37-6

Notes: Nervonic acid (24:1n-9) is a very long chain fatty acid produced by elongation of oleic acid (18:1n-9) (Item No. 90260) and derived from erucic acid (22:1n-9) (Item No. 90175).{21960} It is enriched in nervous tissue and is particularly abundant in sphingolipids, such as sphingomyelin in the myelin sheath of nerve fibers.{21957} Nervonic acid is poorly produced in demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, suggesting that dietary supplementation may be beneficial.{21959} In addition, it is deficient in mice which are homozygous for the quaking mutation, a model of Parkinson’s disease.{21955,21956} Nervonic acid also binds and inhibits DNA polymerase β (Ki = 4.0 uM) and HIV-1 reverse transcriptase (Ki = 1.2 µM).{21958}

• SKU: CAY13940-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 13940-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK