Formulation: A solid
Formal Name: (3α,5β,7β)-3,7-dihydroxy-24-norcholan-23-oic acid
Purity: ≥98%
Formula Markup: C23H38O4
Formula Weight: 378,6
Shelf life (days): 1460
CAS Number: 99697-24-2
Notes: Norursodeoxycholic acid (norUDCA) is a bile acid and the C23 homolog of UDCA (Item No. 15121).{54967,54966} Unlike UDCA, norUDCA does not undergo conjugation to taurine or glycine and is secreted in an unchanged form, as trihydroxy derivatives, or as sulfate or glucuronide conjugates. Dietary administration of norUDCA (0.5% w/w) decreases serum levels of alanine aminotransferase (ALT) and alkaline phosphatase, markers of cholestasis, periductal fibrosis, and hepatic hydroxyproline content in an Mdr2-/- mouse model of sclerosing cholangitis.{54967}