Oleoyl Serotonin-d17

Formulation: A solution in ethanol

Formal Name: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-9Z-11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d17 octadecenamide

Purity: ≥99% deuterated forms (d1-d17)

Formula Markup: C28H27D17N2O2

Formula Weight: 457,8

Shelf life (days): 365

Notes: Oleoyl serotonin-d17 contains 17 deuterium atoms at the 11, 11’, 12, 12’, 13, 13’, 14, 14’, 15, 15’, 16, 16’, 17, 17’, 18, 18, and 18 positions. It is intended for use as an internal standard for the quantification of oleoyl serotonin by GC- or LC-mass spectrometry. Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Item No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} Oleoyl Serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM).{18121}

• SKU: CAY9000694-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 9000694-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung