Formulation: A solution in ethanol
Formal Name: 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine-9,9,10,10-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C28H54D4NO7P
Formula Weight: 555,7
Shelf life (days): 730
Notes: PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of PAF C-18 by GC- or LC-mass spectrometry. PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.{939} It is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages.{3786} PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and enhances the spreading of plated macrophages.{640} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}
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