Formulation: An oil
Formal Name: (9Z)-hexadecenoic-11,11,12,12,13,13,14,14,15,15,16,16,16-d13 acid
Purity: ≥99% deuterated forms (d1-d13)
Formula Markup: C16H17D13O2
Formula Weight: 267,5
Shelf life (days): 1460
CAS Number: 2692623-92-8
Notes: Palmitoleic acid-d13 is intended for use as an internal standard for the quantification of palmitoleic acid (Item Nos. 10009871 / 21911) by GC- or LC-MS. Palmitoleic acid is an ω-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils.{14132,14133} It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM.{52425} Ex vivo, palmitoleic acid (300 mg/kg per day) increases glucose uptake and aerobic and anaerobic glycolysis and reduces de novo fatty acid synthesis and activity of the lipogenic enzymes ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH) in isolated murine adipocytes. Dietary administration of palmitoleic acid (300 mg/kg) reduces high-fat diet-induced insulin resistance and liver inflammation in mice.{52426}