Formulation: A solution in ethanol
Formal Name: 7R-[(1,9-dioxononyl)oxy]-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphapentacosan-1-aminium, 4-oxide, inner salt
Purity: ≥95%
Formula Markup: C33H64NO9P
Formula Weight: 649,4
Shelf life (days): 365
CAS Number: 135726-46-4
Notes: PON-PC is an oxidized phospholipid containing a truncated 9-carbon fatty acyl chain terminating in an aldehyde at the sn-2 position.{61446,61447} It is a component of oxidized LDL formed by oxidation of palmitoyl oleoyl phosphatidylcholine (POPC) and can also be formed via a reaction with ozone in pulmonary surfactant.{61446,61447,61448} PON-PC decreases the production of TNF-α, nitric oxide (NO), and NADP+ in primary mouse alveolar macrophages, as well as reduces the bactericidal activity of RAW 264.7 cells, when used at a concentration of 40 µM.{61446} Bronchoalveolar lavage fluid (BALF) levels of PON-PC are elevated in mice exposed to cigarette smoke and in aged mice.{61447,61449}
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