Formulation: A crystalline solid
Formal Name: (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol
Purity: ≥98%
Formula Markup: C30H26O12
Formula Weight: 578,5
Shelf life (days): 1460
CAS Number: 29106-49-8
Notes: Procyanidin B2 is a phenol and a dimer of (–)-epicatechin (Item No. 11807) that has been found in apple pomace and has diverse biological activities.{54438,54439,54440,54441} It inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM).{54438} Procyanidin B2 scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and superoxide anion radicals in cell-free assays.{54439} It inhibits LDL oxidation in vitro by 79.5 and 98% when used at concentrations of 5 and 10 µM, respectively.{54440} Procyanidin B2 (100 mg/kg) prevents carbon tetrachloride-induced increases in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities and hepatic injury in mice.{54441}
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