Formulation: A solution in methyl acetate
Formal Name: 9-oxo-15S-hydroxy-prosta-5Z,10,13E,17Z-tetraen-1-oic acid
Purity: ≥98%
Formula Markup: C20H28O4
Formula Weight: 332,4
Shelf life (days): 365
CAS Number: 36614-31-0
Notes: Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles{963} and in the ocular tissues of primates.{1144} Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively, in a radioligand binding assay.{11147,11148} PGA3 has weak affinity for human PPARγ, with a Ki value of 188 µM.{11138}