Formulation: A solution in ethanol
Formal Name: 9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic N-[2-(3,4-dihydroxyphenyl)ethyl amide
Purity: ≥95%
Formula Markup: C28H41NO6
Formula Weight: 487,6
Shelf life (days): 365
Notes: Prostaglandin D2 (PGD2; Item No. 12010), the major eicosanoid product of mast cells in the immune system, is also produced in the brain where it is involved in sleep regulatory mechanisms.{416,29764} Further pharmacological actions include inhibition of platelet aggregation, relaxation of vascular smooth muscle, and regulation of reproductive development.{580} Dopamine-containing neurons in the brain are involved in reward-motivated behavior, motor control, and hormone release.{29765} Peripheral, paracrine actions of dopamine include the control of vasodilation, sodium excretion, insulin production, gastrointestinal motility, and the activity of lymphocytes.{29764,5481} Catecholamines are known to stimulate prostanoid synthesis by acting as co-substrates.{2460} PGD2 dopamine is a conjugate of the neurotransmitter dopmaine and PGD2. It can be used to study the biological function of PGD2 in the brain and periphery.
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