Formulation: A solution in methyl acetate
Formal Name: 11α,15S-dihydroxy-9-oxo-prost-13E-en-1-oic acid, ethyl ester
Purity: ≥95%
Formula Markup: C22H38O5
Formula Weight: 382,5
Shelf life (days): 730
CAS Number: 35900-16-4
Notes: Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid.{5702} Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 value of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM.{960,1751} PGE1 is used to treat male erectile dysfunction and to maintain ductus arteriosus patency in infants.{3468,5876} PGE1 ethyl ester is an esterified form of the free acid which may be more amenable for certain applications.