Formulation: A solution in methyl acetate
Formal Name: 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, methyl ester
Purity: ≥98%
Formula Markup: C21H34O5
Formula Weight: 366,5
Shelf life (days): 365
CAS Number: 31753-17-0
Notes: Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 (Item No. 14010) with enhanced lipid solubility. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Item No. 90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.{1585,1558,437,1330} The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.{1422} Affinity constants (Kd) values of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.{1422}
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