Formulation: A solution in ethanol
Formal Name: 11α,15S-dihydroxy-9-oxo-prosta-52,13E-dien-1-oyl-polyethylene glycol 11-N’-biotinoyl-1,5-diaminopentane
Purity: ≥98%
Formula Markup: C54H96N4O17S
Formula Weight: 1105,4
Shelf life (days): 365
Notes: PGE2 is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others. PGE2 contracts smooth muscle, protects the gastric mucosa, modulates immune function, and regulates fertility and implantation. PGE2 acts through at least four G-protein coupled receptors, EP1-EP4. PGE2-PEG11-biotin is an affinity probe which allows PGE2 to be detected or immobilized using the biotin ligand. The PEG11 moiety serves to separate the biotin linker from PGE2 with a hydrophilic spacer. It is thus a tool to be used in the elucidation of PGE2 actions or interactions in aqueous solutions.
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