Formulation: A solution in ethanol
Formal Name: 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester
Purity: ≥98% (as a 9:1 mixture of the 2- and 1-glyceryl esters)
Formula Markup: C23H40O7
Formula Weight: 428,6
Shelf life (days): 365
CAS Number: 43042-79-1
Notes: 2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.{10555}
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