Prostaglandin H1, CAS 52589-22-7

Formulation: A solution in acetone

Formal Name: 9α,11α-epidioxy-15S-hydroxy-prost-13E-en-1-oic acid

Purity: ≥95%

Formula Markup: C20H34O5

Formula Weight: 354,5

Shelf life (days): 730

CAS Number: 52589-22-7

Notes: Prostaglandin H1 (PGH1) is the unstable precursor to all 1-series PGs and thromboxanes.{500,69145,11296} It is produced from dihomo-γ-linolenic acid (DGLA; Item No. 90230) by COX-1 and COX-2. {69146,69145} PGH1 is an agonist of the PGD2 receptor CRTH2.{69147} It increases intracellular calcium levels in HEK293 cells expressing CRTH2 when used at a concentration of 3 µM and induces CRTH2 internalization at 1 µM, an effect that can be blocked by the CRTH2 antagonist TM30089 (CAY10471; Item No. 10006735). PGH1 is also a suicide inhibitor of platelet thromboxane synthase (Ki = 28 µM).{49}

• SKU: CAY17015-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17015-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK