Formulation: A solution in methyl acetate
Formal Name: (Z)-7-((1S,5R)-5-((S,E)-3-hydroxyoct-1-en-1-yl)-4-oxocyclopent-2-en-1-yl)hept-5-enoic-3,3,4,4-d4 acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C20H26D4O4
Formula Weight: 338,5
Shelf life (days): 730
CAS Number: 2738376-80-0
Notes: Prostaglandin J2-d4 is intended for use as an internal standard for the quantification of prostaglandin J2 (Item No. 18500) by GC- or LC-MS. Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin.{1742} PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM.{1139,504} PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines.{870} However, this activity has been attributed to further metabolites of PGJ2 and not the parent compound itself.
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