Formulation: A lyophilized powder
Formal Name: 1-(1,2R-dioctanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt
Purity: ≥97%
Formula Markup: C25H46O19P3 • 3Na
Formula Weight: 812,5
Shelf life (days): 1825
Notes: The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{243,8344} PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.