Formulation: A solution in ethanol
Formal Name: 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid, methyl ester
Purity: ≥97%
Formula Markup: C23H34O5
Formula Weight: 390,5
Shelf life (days): 365
CAS Number: 937738-63-1
Notes: Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
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