Formulation: A solution in ethanol
Formal Name: 7S,16R,17S-trihydroxy-8E,10Z,12E,14E,19Z-docosapentaenoic acid
Purity: ≥98%
Formula Markup: C22H34O5
Formula Weight: 378,5
Shelf life (days): 365
CAS Number: 2093111-29-4
Notes: Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).{33485} It is formed from docosapentaenoic acid (n-3 DPA; Item Nos. 90165 / 21907), an intermediate in the conversion of eicosapentaenoic acid (Item Nos. 90110 / 90110.1 / 21908) to docosahexaenoic acid (Item Nos. 90310 / 17950), in human leukocytes. RvD2 n-3 DPA (1 nM) reduces TNF-α-induced chemotaxis and adhesion of isolated human neutrophils. In vivo, RvD2 n-3 DPA (100 ng/animal; i.v.) reduces peritoneal neutrophil infiltration and exudate levels of IL-6 and chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of zymosan-induced inflammation.
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