Formulation: A solution in ethanol
Formal Name: (4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxy-6,8,10,13,15,19-docosahexaenoic acid
Purity: ≥95%
Formula Markup: C22H32O5
Formula Weight: 376,5
Shelf life (days): 365
CAS Number: 1025684-60-9
Notes: Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
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