Formulation: A lyophilisate
Formal Name: butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-(3-methylbutyl)-1,7-dioxaspiro[5.5]undec-3-yl] ester
Purity: ≥95%
Formula Markup: C37H54O11
Formula Weight: 674,8
Shelf life (days): 1460
CAS Number: 144860-69-5
Notes: Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs = 2.0 and >500 µg/ml at pH 3 and 7.4, respectively).{36572,28254} Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line.{28254} It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50 = 1.58 µg/ml) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50 = 2.0 µg/ml for both).{28254}
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