Formulation: A crystalline solid
Formal Name: 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C16H12O7
Formula Weight: 316,3
Shelf life (days): 1460
CAS Number: 90-19-7
Notes: Rhamnetin is a flavonoid that has been found in O. falcate and has diverse biological activities.{61082,33775,33776,33774} It reduces production of reactive oxygen species (ROS) and apoptosis induced by miconazole (Item No. 15420) in H9c2 cardiomyocytes.{33775} Rhamnetin inhibits LPS-induced TNF-α and nitric oxide (NO) production in rat neonatal organotypic hippocampal slice cultures (OHSCs) under control conditions and during ethanol withdrawal, as well as NMDA-induced neurotoxicity in OHSCs undergoing ethanol withdrawal.{33776} Dietary administration of rhamnetin (0.1 and 0.2% w/w) reduces serum levels of malondialdehyde (MDA) and liver and erythrocyte levels of thiobarbituric acid reactive substances (TBARS) in rats fed a cholesterol-free diet.{33774} Rhamnetin increases time spent in the target quadrant in the Morris water maze in a rat model of traumatic brain injury.{33777}