Formulation: A neat oil
Formal Name: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene
Purity: ≥95%
Formula Markup: C30H50
Formula Weight: 410,7
Shelf life (days): 1460
CAS Number: 111-02-4
Notes: Squalene is a biosynthetic precursor to all steroids and a terpene originally isolated from shark liver oil.{45222,45221} Squalene is produced in mammals by condensation of two farnesyl diphosphate molecules by squalene synthase and then oxidized to squalene epoxide for use in the biosynthesis of lanosterol (Item No. 19521), cholesterol, and other steroids.{45222} An oil-in-water emulsion of squalene synergistically increases adaptive immune responses to glucopyranosyl lipid adjuvant (GLA), a toll-like receptor 4 (TLR4) agonist, compared with an aqueous formulation of GLA.{45223} Formulations containing squalene have been used as adjuvants in vaccines and as hair and skin conditioning agents.
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