Tauro-β-muricholic Acid (sodium salt), CAS 145022-92-0

Formulation: A crystalline solid

Formal Name: 2-[[(3α,5β,6β,7β)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt

Purity: ≥95%

Formula Markup: C26H44NO7S • Na

Formula Weight: 537,7

Shelf life (days): 730

CAS Number: 145022-92-0

Notes: Tauro-β-muricholic acid (TβMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR; IC50 = 40 µM) and a taurine-conjugated form of the murine-specific primary bile acid β-muricholic acid (Item No. 20287).{33771} TβMCA accumulates in germ-free mice under normal conditions but is reduced after colonization with feces from a human donor.{33771,33772} TβMCA is increased in the intestines of mice resistant to high-fat diet-induced obesity, fatty liver, and diabetes.{33770}

• SKU: CAY20289-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 20289-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK