Formulation: A crystalline solid
Formal Name: 2-[[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt
Purity: ≥95%
Formula Markup: C26H44NO6S • Na
Formula Weight: 521,7
Shelf life (days): 1460
CAS Number: 38411-85-7
Notes: Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid (Item No. 20294).{39310} THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.{39309} Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; Item No. 20275) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.{39311} THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.{39312}
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