Taurolithocholic Acid (sodium salt), CAS 6042-32-6

Formulation: A crystalline solid

Formal Name: 2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt

Purity: ≥95%

Formula Markup: C26H44NO5S • Na

Formula Weight: 505,7

Shelf life (days): 1460

CAS Number: 6042-32-6

Notes: Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acid (Item No. 20253).{33902} TLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells.{28235} It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis.{28234,43818} Serum levels of TLCA increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.{33902}

• SKU: CAY17275-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17275-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK