Formulation: A solution in methanol at 100 µg/ml
Formal Name: 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl-2,2,3,4,4-d4]amino]-ethanesulfonic acid
Purity: ≥95%
Formula Markup: C26H41D4NO6S
Formula Weight: 503,7
Shelf life (days): 1825
CAS Number: 2410279-94-4
Notes: Tauroursodeoxycholic acid-d4 (TUDCA-d4) is intended for use as an internal standard for the quantification of tauroursodeoxycholic acid (Item Nos. 20277 / 9003379) by GC- or LC-MS. TUDCA is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Item No. 15121).{25912,32137} TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears.{32137} It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's disease, ischemic brain injury, and retinal disorders.{32138,32137} TUDCA-d4 MaxSpec® Standard is a quantitative grade standard of TUDCA-d4 (Item No. 32985) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. The verified concentration is provided on the certificate of analysis. This TUDCA-d4 MaxSpec® standard is guaranteed to meet identity, purity, and stability specifications and is provided with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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