Formulation: A crystalline solid
Formal Name: N-[2-(1H-indol-2-yl)-2-oxoethyl]-9Z,12Z-octadecadienamide
Purity: ≥97%
Formula Markup: C28H40N2O2
Formula Weight: 436,6
Shelf life (days): 730
CAS Number: 1254277-89-8
Notes: Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson’s, Alzheimer’s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.{20216}
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