Formulation: A crystalline solid
Formal Name: N-[2-(4-hydroxyphenyl)ethyl]-9Z,12Z-octadecadienamide
Purity: ≥98%
Formula Markup: C26H41NO2
Formula Weight: 399,6
Shelf life (days): 730
CAS Number: 1177258-62-6
Notes: Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson’s, Alzheimer’s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites. Termitomycamide E is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.{20216}
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