Tigogenin, CAS 77-60-1

Formulation: A solid

Formal Name: (3β,5α,25R)-spirostan-3-ol

Purity: ≥90%

Formula Markup: C27H44O3

Formula Weight: 416,6

Shelf life (days): 1460

CAS Number: 77-60-1

Notes: Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities.{38813,46840,46841,46842} It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner.{46840} It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC50 = 16 μg/ml).{46841} It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.{46842}

• SKU: CAY30137-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30137-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK