Formulation: A crystalline solid
Formal Name: (E)-octadec-11-enoic-13,13,14,14,15,15,16,16,17,17,18,18,18-d13 acid
Purity: ≥99% deuterated forms (d1-d13)
Formula Markup: C18H21D13O2
Formula Weight: 295,5
Shelf life (days): 1460
Notes: trans-Vaccenic acid-d13 is intended for use an internal standard for the quantification of trans-vaccenic acid (Item No. 15301) by GC- or LC-MS. trans-Vaccenic acid is an ω-7 fatty acid that has been found in bovine milk fats.{25285} Dietary administration of trans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome.{52757} It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice.{25287}