Formulation: A solid
Formal Name: 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C17H14O7
Formula Weight: 330,3
Shelf life (days): 1460
CAS Number: 520-32-1
Notes: Tricin is a flavone that has been found in O. sativa and has diverse biological activities.{68396,68394,68395,68397} It scavenges ABTS (Item No. 27317) radicals in a cell-free assay (IC50 = 0.312 mg/ml).{68396} Tricin (0.1-10 µM) reduces virus titer and expression of the human cytomegalovirus (HCMV) genes IE1 and UL54 in HCMV-infected human embryonic lung fibroblast (HEL) cells, an effect that can be reversed by overexpression of chemokine (C-C motif) ligand 2 (CCL2).{68394} It inhibits IgE-induced degranulation of RBL-2H3 cells (IC50 = 4.83 µM).{68395} In vivo, tricin (37.5 mg/kg per day) reduces tumor growth and the number of lung metastases in a CT26 murine colon carcinoma model.{68397}
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