Formulation: A solid
Formal Name: 3β-(α-L-arabinopyranosyloxy)-19-hydroxy-urs-12-en-28-oic acid
Purity: ≥98%
Formula Markup: C35H56O8
Formula Weight: 604,8
Shelf life (days): 1460
CAS Number: 35286-59-0
Notes: Ziyuglycoside II is a steroid glycoside that has been found in S. officinalis and has diverse biological activities.{72396,72397,72398} It is cytotoxic to SMMC-7721, PC-9, HCT116, MCF-7, and MDA-MB-231 cancer cells when used at concentrations of 30 and 90 µg/ml.{72396} Ziyuglycoside II (6, 12, and 18 mg/kg) increases the number of white blood cells in peripheral blood and the number of hematopoietic stem and progenitor cells (HSPCs) in a mouse model of leukopenia induced by the nitrogen mustard alkylating agent cyclophosphamide (Item No. 13849).{72397} It also reduces small intestinal epithelial cell apoptosis and IL-1β, IL-6, and TNF-α levels, as well as improves diarrhea symptoms in a mouse model of rotavirus-induced diarrhea.{72398}
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