Formulation: A solid
Formal Name: (3S,3aR,9aR)-3a,4,8,9a-tetrahydro-3-(1-hydroxyhexyl)-9a-methyl-6-(1E)-1-propen-1-yl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
Purity: ≥95%
Formula Markup: C21H28O5
Formula Weight: 360,4
Shelf life (days): 1460
CAS Number: 1011244-19-1
Notes: Monascuspiloin is a fungal metabolite that has been found in M. pilosus M93-fermented rice.{61244} It induces endoplasmic reticulum stress and autophagy in PC3 prostate cancer cells. Monascuspiloin (15-45 µM) decreases viability of PC3 cells and has an additive effect on the reduction in viability of PC3 cells induced by irradiation when used at a concentration of 25 µM. It induces intratumor apoptosis and autophagy and reduces tumor growth in a PC3 mouse xenograft model when administered at doses of 40 and 120 mg/kg.{61245}