N-Desethylamiodarone (hydrochloride), CAS 96027-74-6

N-Desethylamiodarone (hydrochloride), CAS 96027-74-6
SKU
CAY9000537-50
Packaging Unit
50 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-methanone, monohydrochloride

Purity: ≥95%

Formula Markup: C23H25I2NO3 • HCl

Formula Weight: 653,7

Shelf life (days): 730

CAS Number: 96027-74-6

Notes: Amiodarone (Item No. 15213) is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents.{22478} It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM.{24593} In humans, cytochrome P450 3A is involved in the metabolism of amiodarone.{29074} N-Desethylamiodarone is the major, active metabolite of amiodarone. This compound has been used as an analytical reference standard for quantifying amiodarone in plasma samples.{29075}
More Information
SKU CAY9000537-50
Manufacturer Cayman Chemical
Manufacturer SKU 9000537-50
Package Unit 50 mg
Quantity Unit STK
Application Reinstoffe, Isotopenmarkierung
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