Product Description: 1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C21H22O5
References: [1]Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63. /[2]Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6./[3]Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597.
CAS Number: 65428-13-9
Molecular Weight: 354.40
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Bacterial;Endogenous Metabolite
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