10'-Desmethoxystreptonigrin, CAS 136803-89-9

Product Description: 10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg)[1].

Formula: C24H20N4O7

References: [1]Liu WC, et al. 10'-Desmethoxystreptonigrin, a novel analog of streptonigrin. J Antibiot (Tokyo). 1992 Apr;45(4):454-7.

CAS Number: 136803-89-9

Molecular Weight: 476.44

Research Area: Cancer; Infection

Target: Antibiotic;Bacterial;Farnesyl Transferase

• SKU: MEXHY-137139-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-137139-0
• Package Unit: Get quote
• Quantity Unit: STK