(±)-10-Hydroxycamptothecin, CAS 64439-81-2

Product Description: (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.

Applications: Cancer-programmed cell death

Formula: C20H16N2O5

References: [1]Liu SY, et al. Interaction of several nucleoside triphosphate analogues and 10-hydroxycamptothecin with human DNA topoisomerases. Cancer Res. 1989 Mar 15;49(6):1366-70./[2]Ping YH, et al. Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer. Oncol Rep. 2006 May;15(5):1273-9./[3]Fan J, et al. Detection of apoptosis exposed to 10-hydroxycamptothecin in T24 human urinary bladder cancer cells. Zhonghua Wai Ke Za Zhi. 1999 Jan;37(1):57-9.

CAS Number: 64439-81-2

Molecular Weight: 364.35

Compound Purity: 99.57

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Topoisomerase

• SKU: MEXHY-N0275-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0275-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK