14-Deoxyandrographolide, CAS 4176-97-0

Product Description: 14-Deoxyandrographolide is a labdane diterpene with calcium channel blocking activity. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20H30O4

References: [1]Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43./[2]Burgos RA, et al. Effect of 14-deoxyandrographolide on calcium-mediated rat uterine smooth muscle contractility. Phytother Res. 2003;17(9):1011-1015.

CAS Number: 4176-97-0

Molecular Weight: 334.45

Compound Purity: 99.47

Research Area: Metabolic Disease; Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Calcium Channel

• SKU: MEXHY-N4323-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N4323-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK