16-Hydroxycleroda-3,13-dien-15,16-olide, CAS 141979-19-3

Product Description: 16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C20H30O3

References: [1]Po-Kai Huang, et al. Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4. Int J Mol Sci. 2019 Jan 27;20(3):530.

CAS Number: 141979-19-3

Molecular Weight: 318.45

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Dipeptidyl Peptidase

• SKU: MEXHY-N9725-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N9725-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK